- The lines have been posted for Week 1 of the NFL preseason
- The defending Super Bowl-champion Tampa Bay Buccaneers are six-point favorites over the Cincinnati Bengals
- All the odds can be found below along with some best bets for preseason Week 1
A full weekend of NFL preseason games is on tap for the first time since 2019.
All 32 teams will be in action beginning Thursday night. That comes a year after the entire exhibition season was cancelled because of the COVID-19 pandemic.
The 2021 preseason got underway last Thursday when the Pittsburgh Steelers beat the Dallas Cowboys 16-3 in the Hall of Fame Game in Canton. The table below shows the NFL odds for all 16 upcoming Week 1 games.
NFL Preseason Week 1 Odds
| Team | Moneyline | Spread | Over/Under |
|---|---|---|---|
| Washington Football Team | -135 | -2.5 (-105) | Over 35.5 (-110) |
| New England Patriots | +115 | +2.5 (-115) | Under 35.5 (-110) |
| Team | Moneyline | Spread | Over/Under |
| Pittsburgh Steelers | +100 | +1 (-110) | Over 34 (-110) |
| Philadelphia Eagles | -120 | -1 (-110) | Under 34 (-110) |
| Team | Moneyline | Spread | Over/Under |
| Tennessee Titans | -120 | -1 (-110) | Over 38 (-110) |
| Atlanta Falcons | +100 | +1 (-110) | Under 38 (-110) |
| Team | Moneyline | Spread | Over/Under |
| Buffalo Bills | -130 | -2.5 (-105) | Over 37 (-110) |
| Detroit Lions | +110 | +2.5 (-115) | Under 37 (-110) |
| Team | Moneyline | Spread | Over/Under |
| Dallas Cowboys | +100 | +1.5 (-115) | Over 40 (-110) |
| Arizona Cardinals | -120 | -1.5 (-105) | Under 40 (-110) |
| Team | Moneyline | Spread | Over/Under |
| Miami Dolphins | +155 | +3.5 (-110) | Over 34.5 (-110) |
| Chicago Bears | -180 | -3.5 (-110) | Under 34.5 (-110) |
| Team | Moneyline | Spread | Over/Under |
| Denver Broncos | -120 | -1 (-115) | Over 34.5 (-110) |
| Minnesota Vikings | +100 | +1 (-105) | Under 34.5 (-110) |
| Team | Moneyline | Spread | Over/Under |
| New Orleans Saints | +120 | +2.5 (-110) | Over 35.5 (-115) |
| Baltimore Ravens | -140 | -2.5 (-110) | Under 35 (-105) |
| Team | Moneyline | Spread | Over/Under |
| Cleveland Browns | +100 | +1 (-110) | Over 37.5 (-105) |
| Jacksonville Jaguars | -120 | -1 (-110) | Under 37.5 (-115) |
| Team | Moneyline | Spread | Over/Under |
| Cincinnati Bengals | +200 | +6 (-110) | Over 33.5 (-110) |
| Tampa Bay Buccaneers | -240 | -6 (-110) | Under 33.5 (-110) |
| Team | Moneyline | Spread | Over/Under |
| New York Jets | +105 | +1.5 (-105) | Over 34.5 (-115) |
| New York Giants | -125 | -1.5 (-115) | Under 34.5 (-105) |
| Team | Moneyline | Spread | Over/Under |
| Houston Texans | +125 | +3 (-110) | Over 33.5 (-115) |
| Green Bay Packers | -150 | -3 (-110) | Under 33.5 (-105) |
| Team | Moneyline | Spread | Over/Under |
| Kansas City Chiefs | +110 | +1.5 (-105) | Over 36.5 (-115) |
| San Francisco 49ers | -130 | -1.5 (-115) | Under 36.5 (-105) |
| Team | Moneyline | Spread | Over/Under |
| Seattle Seahawks | +105 | +1.5 (-110) | Over 37.5 (-110) |
| Las Vegas Raiders | -125 | -1.5 (-110) | Under 37.5 (-110) |
| Team | Moneyline | Spread | Over/Under |
| Los Angeles Chargers | -160 | -2.5 (-120) | Over 34.5 (-115) |
| Los Angeles Rams | +135 | +2.5 (-100) | Under 34.5 (-105) |
| Team | Moneyline | Spread | Over/Under |
| Carolina Panthers | +105 | +2 (-110) | Over 34.5 (-110) |
| Indianapolis Colts | -125 | -2 (-110) | Under 34.5 (-110) |